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3-Hydroxy-6-methyl-5-methoxy-2-pentyl-4H-pyran-4-one 125263-70-9 manufacturer CAS NO.125263-70-9
- Min.Order: 10 Metric Ton
- Payment Terms: L/C,T/T,Other
- Product Details
Keywords
- 125263-70-9 manufacturer
- 3-Hydroxy-6-methyl-5-methoxy-2-pentyl-4H-pyran-4-one
- 125263-70-9 fast delivery
Quick Details
- ProName: 3-Hydroxy-6-methyl-5-methoxy-2-pentyl-...
- CasNo: 125263-70-9
- Molecular Formula: C12H18O4
- Appearance: Powder or liquid
- Application: Medicinal Chemistry Biomedicine Phar...
- DeliveryTime: Goods in stock
- PackAge: According to customer
- Port: Shanghai
- ProductionCapacity: Metric Ton/Day
- Purity: 97%
- Storage: Store in a tightly closed container, i...
- Transportation: Fedex,DHL,TNT,BY SEA and BY AIR
- LimitNum: 10 Metric Ton
- Moisture Content: 5%
- Grade: Industrial Grade，Reagent Grade
Superiority
Allixin is a phytoallexin found in garlic (Allium sativum) bulbs. Allixin has weak antimicrobial activity and exerts an anti-promoting activity against skin tumors induced by the chemical 12-O-tetradecanoylphorbol-13-acetate (TPA). Allixin also demonstrates an inhibitory effect on aflatoxin B1-induced mutagenesis.
Allixin is a phytoallexin found in garlic (Allium sativum) bulbs. It was first isolated and characterized in 1989. When garlic is stored for long periods of time, it can form visible accumulations of crystalline allixin on its surface, particularly in areas where tissue has become necrotic. After 2 years of storage, the amount of allixin accumulated can approach 1% of the dry weight of the cloves. Since allixin has weak antimicrobial activity,these high concentrations are thought to be produced by the garlic bulb to protect itself from further damage from microorganisms.
Details
In in vitro studies, allixin demonstrates neurotrophic activity, but at high concentrations it has cytotoxic effects. Simple chemical analogs of allixin were found to have more potent neurotrophic activity, but without the cytotoxic effects.Allixin may therefore be a useful starting point for the development of pharmaceutical drugs for the treatment of neurodegenerative disorders or for neuronal regeneration in the brain.
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